HES5 anticorps (N-Term)
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- Antigène Voir toutes HES5 Anticorps
- HES5 (Hairy and Enhancer of Split 5 (HES5))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HES5 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- HES5 antibody is human, mouse and rat reactive. At least two isoforms of HES5 are known to exist, this antibody will detect both isoforms.
- Purification
- HES5 antibody is affinity chromatography purified via peptide column.
- Immunogène
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HES5 antibody was raised against a 19 amino acid peptide near the amino terminus of human HES5.
The immunogen is located within the first 50 amino acids of HES5. - Isotype
- IgG
- Top Product
- Discover our top product HES5 Anticorps primaire
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- Indications d'application
- HES5 antibody can be used for detection of HES5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- HES5 antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- HES5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- HES5 (Hairy and Enhancer of Split 5 (HES5))
- Autre désignation
- HES5 (HES5 Produits)
- Synonymes
- anticorps fk51a02, anticorps her15, anticorps hes5, anticorps wu:fk51a02, anticorps zgc:136520, anticorps bHLHb38, anticorps hairy and enhancer of split-related 15, tandem duplicate 1, anticorps hes family bHLH transcription factor 5, anticorps hairy and enhancer of split 5 (Drosophila), anticorps transcription factor HES-5-like, anticorps her15.1, anticorps HES5, anticorps hes5, anticorps LOC100221262, anticorps LOC100226434, anticorps Hes5
- Sujet
- HES5 is a member of the HES family of transcriptional repressors, which are the mammalian homologs of the Drosophila Hairy and Enhancer of Split and contain basic Helix-loop-helix (bHLH) and Orange domains (1). The HES5 gene is a downstream target of the Notch signaling pathway and its expression is downregulated during human cartilage differentiation (2). HES5 can directly repress transcription of the E3 ligase FBW7-beta, creating a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions (3).
- Poids moléculaire
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Predicted: 18 kDa
Observed: 17 kDa - ID gène
- 388585
- NCBI Accession
- NP_001010926
- UniProt
- Q5TA89
- Pathways
- Stem Cell Maintenance, Tube Formation
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