STAT2 anticorps
Aperçu rapide pour STAT2 anticorps (ABIN5692942)
Antigène
Voir toutes STAT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Anti-STAT2 Antibody
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Séquence
- FQDQLHQLYS HSLLPVDIRQ YLAVWIEDQN WQEA
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-STAT2 Antibody (ABIN5692942). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human STAT2, which shares 73.5% and 76.5% amino acid (aa) sequence identity with mouse and rat STAT2, respectively.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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Autre désignation
- STAT2
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Sujet
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Synonyms: Signal transducer and activator of transcription 2, p113, STAT2
Background: Signal transducer and activator of transcription 2 (STAT2) is a protein that in humans is encoded by the STAT2 gene. The protein encoded by this gene is a member of the STAT protein family. The International Radiation Hybrid Mapping Consortium mapped the STAT2 gene to chromosome 12. STAT2 is a transcription factor critical to the signal transduction pathway of type I interferons. ISGF3 (STAT2) assembly involves p48 functioning as an adaptor protein to recruit Stat1 and Stat2 to an IFN-alpha-stimulated response element, Stat2 contributes a potent transactivation domain but is unable to ly contact DNA, while Stat1 stabilizes the heteromeric complex by contacting DNA ly.
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Poids moléculaire
- 113 kDa
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ID gène
- 6773
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UniProt
- P52630
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Pathways
- Signalistation JAK/STAT, Hepatitis C, CXCR4-mediated Signaling Events
Antigène
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