BIRC2 anticorps (AA 320-570)

N° du produit ABIN5693185

Détail du produit anti-BIRC2 anticorps

Antigène: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Épitope: AA 320-570

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC2 est non-conjugé

Application: Western Blotting (WB), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for cIAP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human cIAP1 recombinant protein (Position: D320-T570).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur BIRC2

Antigène: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Autre désignation: BIRC2 (BIRC2 Produits)

Synonymes: anticorps API1, anticorps HIAP2, anticorps Hiap-2, anticorps MIHB, anticorps RNF48, anticorps c-IAP1, anticorps cIAP1, anticorps Api2, anticorps rIAP1, anticorps IAP1, anticorps ITA, anticorps AW146227, anticorps Api1, anticorps Birc3, anticorps HIAP1, anticorps IAP2, anticorps MIAP1, anticorps MIAP2, anticorps MIHC, anticorps cIAP2, anticorps mcIAP1, anticorps ciap-1, anticorps birc3, anticorps api1, anticorps birc2, anticorps c-iap1, anticorps ciap1, anticorps hiap-2, anticorps hiap2, anticorps mihb, anticorps rnf48, anticorps baculoviral IAP repeat containing 2, anticorps baculoviral IAP repeat-containing 2, anticorps baculoviral IAP repeat containing 2 L homeolog, anticorps BIRC2, anticorps Birc2, anticorps birc2, anticorps birc2.L

Sujet:

Synonyms: Baculoviral IAP repeat-containing protein 2

Tissue Specificity: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.

Background: Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q13490

Pathways: Apoptose, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades