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Prothrombin anticorps (AA 67-124)

F2 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5693261
  • Antigène Voir toutes Prothrombin (F2) Anticorps
    Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
    Épitope
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 67-124
    Reactivité
    • 44
    • 26
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 15
    • 9
    • 5
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 66
    • 13
    Polyclonal
    Conjugué
    • 53
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Prothrombin est non-conjugé
    Application
    • 53
    • 28
    • 25
    • 20
    • 14
    • 13
    • 11
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Marque
    Picoband™
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Prothrombin detection. Tested with WB, IHC-P, Direct ELISA in Human.
    Immunogène
    E. coli-derived human Prothrombin recombinant protein (Position: Y67-R124).
    Top Product
    Discover our top product F2 Anticorps primaire
  • Indications d'application

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Application Details: Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Shen, Fang, Lv, Pei, Wang, Jiang, Ding: "Heparin impairs angiogenesis through inhibition of microRNA-10b." dans: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).

  • Antigène
    Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
    Autre désignation
    F2 (F2 Produits)
    Synonymes
    anticorps PT, anticorps RPRGL2, anticorps THPH1, anticorps Cf-2, anticorps Cf2, anticorps FII, anticorps thrombin, anticorps zgc:66319, anticorps wu:fb57c10, anticorps wu:fd42e09, anticorps wu:fd59d01, anticorps prothrombin, anticorps F2, anticorps coagulation factor II, thrombin, anticorps coagulation factor II, anticorps coagulation factor II (thrombin), anticorps F2, anticorps f2
    Sujet

    Synonyms: Prothrombin, Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain, F2

    Tissue Specificity: Expressed by the liver and secreted in plasma.

    Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.

    UniProt
    P00734
    Pathways
    Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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