MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 2-239) anticorps Primary Antibody
- AA 2-239
- Humain, Souris, Rat
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
- Rabbit IgG polyclonal antibody for MRE11 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- E. coli-derived human MRE11 recombinant protein (Position: S2-D239).
- Indications d'application
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5&mu,g/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1&mu,g/mL
Direct ELISA, 0.1-0.5&mu,g/mL
- For Research Use only
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 4 °C,-20 °C
- Stockage commentaire
- At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Autre désignation
- MRE11 (MRE11A Antibody Extrait)
Synonyms: Double-strand break repair protein MRE11, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A, MRE11
Background: Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Réparation de l'ADN