TSHZ3 anticorps

N° du produit ABIN5698742

Détail du produit anti-TSHZ3 anticorps

Antigène: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSHZ3 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: teashirt zinc finger homeobox 3

Isotype: IgG

Information d'application

Indications d'application: WB : 1:200-1:2000

Commentaires:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09046( TSHZ3 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur TSHZ3

Antigène: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Autre désignation: TSHZ3 (ZNF537 Produits)

Synonymes: anticorps ZNF537, anticorps A630038G13Rik, anticorps Tsh3, anticorps Zfp537, anticorps mKIAA1474, anticorps teashirt3, anticorps TSH3, anticorps teashirt zinc finger homeobox 3, anticorps teashirt zinc finger family member 3, anticorps TSHZ3, anticorps Tshz3

Sujet: Synonyms:FLJ54422, KIAA1474, Teashirt homolog 3, TSH3, TSHZ3, Zinc finger protein 537, ZNF537 Background:Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus(nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator(RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.

Poids moléculaire: 87kDa

ID gène: 57616

UniProt: Q63HK5

Pathways: Regulation of Muscle Cell Differentiation