PLCD4 anticorps

N° du produit ABIN5698963

Détail du produit anti-PLCD4 anticorps

Antigène: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCD4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Immunogène: phospholipase C, delta 4

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur PLCD4

Antigène: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Autre désignation: PLCD4 (PLCD4 Produits)

Synonymes: anticorps PLCD4, anticorps PLCL3, anticorps si:dkeyp-84a8.7, anticorps 4921507K24Rik, anticorps phospholipase C eta 1, anticorps phospholipase C delta 4, anticorps phospholipase C, delta 4a, anticorps phospholipase C, delta 4, anticorps phospholipase C delta 4 L homeolog, anticorps PLCH1, anticorps PLCD4, anticorps plcd4a, anticorps plcd4, anticorps Plcd4, anticorps plcd4.L

Sujet: Synonyms: Background:Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

ID gène: 84812

UniProt: Q9BRC7

Pathways: Inositol Metabolic Process