CDK6 anticorps

N° du produit ABIN5699231

L’anticorps Lapin Polyclonal anti-CDK6 a été validé pour WB, IHC, IF, ELISA et IP. Il convient pour détecter CDK6 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CDK6 anticorps (ABIN5699231)

Antigène: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Détail du produit anti-CDK6 anticorps

Fonction: CDK6 antibody

Immunogène: cyclin-dependent kinase 6

Isotype: IgG

Information d'application

Indications d'application: WB : 1:200-1:2000 IP : 1:200-1:1000 IHC : 1:20-1:200 IF : 1:50-1:500

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01561(CDK6 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CDK6

Antigène: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Autre désignation: CDK6

Sujet:

Synonyms: Cyclin-dependent kinase 6|Cell division protein kinase 6|Serine/threonine-protein kinase PLSTIRE|CDK6|CDKN6

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 37-40 kDa

ID gène: 1021

UniProt: Q00534

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases