SNX27 anticorps

N° du produit ABIN5699843

Détail du produit anti-SNX27 anticorps

Antigène: SNX27 (Sorting Nexin 27 (SNX27))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX27 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogène: sorting nexin family member 27

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08090(SNX27 antibody) at dilution of 1:1200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur SNX27

Antigène: SNX27 (Sorting Nexin 27 (SNX27))

Autre désignation: SNX27 (SNX27 Produits)

Synonymes: anticorps MRT1, anticorps MY014, anticorps 5730552M22Rik, anticorps ESTM45, anticorps ESTM47, anticorps R75405, anticorps mKIAA0488, anticorps Mrt1, anticorps sorting nexin family member 27, anticorps SNX27, anticorps Snx27

Sujet: Synonyms:KIAA0488 Background:Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate(PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.

ID gène: 81609

UniProt: Q96L92