CC2D1A anticorps

N° du produit ABIN5700435

Détail du produit anti-CC2D1A anticorps

Antigène: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CC2D1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Immunogène: coiled-coil and C2 domain containing 1A

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01335(CC2D1A antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CC2D1A

Antigène: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Autre désignation: CC2D1A (CC2D1A Produits)

Synonymes: anticorps mrt3, anticorps freud-1, anticorps FREUD-1, anticorps Freud-1/Aki1, anticorps MRT3, anticorps BC016188, anticorps Freud-1, anticorps Tape, anticorps RGD1306108, anticorps coiled-coil and C2 domain containing 1A, anticorps CC2D1A, anticorps cc2d1a, anticorps Cc2d1a

Sujet: Synonyms:AKI1 Background:Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Poids moléculaire: 130 kDa, 104 kDa

ID gène: 54862

UniProt: Q6P1N0