GRB14 anticorps

N° du produit ABIN5700940

Détail du produit anti-GRB14 anticorps

Antigène: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRB14 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogène: growth factor receptor-bound protein 14

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

DU 145 cells were subjected to SDS PAGE followed by western blot with FNab03641( GRB14 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur GRB14

Antigène: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Autre désignation: GRB14 (GRB14 Produits)

Synonymes: anticorps GRB14, anticorps AI505286, anticorps growth factor receptor bound protein 14, anticorps GRB14, anticorps grb14, anticorps Grb14

Sujet: Synonyms: Background:Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor(INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Poids moléculaire: 61 kDa

ID gène: 2888

UniProt: Q14449