PPARA anticorps

N° du produit ABIN5701207

Cet anticorps Lapin Polyclonal détecte spécifiquement PPARA dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PPARA anticorps (ABIN5701207)

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PPARA anticorps

Fonction: PPARA antibody

Immunogène:

Immunogen sequence: 1-468

Immunogen: peroxisome proliferator-activated receptor alpha

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000, IHC: 1:50-1:200

Commentaires:

U-937 cells were subjected to SDS PAGE followed by western blot with FNab06663(PPARA antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PPARA

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Autre désignation: PPARA

Sujet:

Synonyms: Peroxisome proliferator-activated receptor alpha (PPAR-alpha)|Nuclear receptor subfamily 1 group C member 1|PPARA|NR1C1|PPAR

Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Poids moléculaire: 52-55 kDa

ID gène: 5465

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C