FKBP6 anticorps

N° du produit ABIN5702833

Détail du produit anti-FKBP6 anticorps

Antigène: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Immunogène: FK506 binding protein 6, 36kDa

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur FKBP6

Antigène: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Autre désignation: FKBP6 (FKBP6 Produits)

Synonymes: anticorps 1700008G22Rik, anticorps 36kDa, anticorps AU017274, anticorps D5Ertd724e, anticorps FKBP-36, anticorps FKBP-6, anticorps PPiase, anticorps FKBP36, anticorps FK506 binding protein 6, anticorps FK506 binding protein 6 L homeolog, anticorps Fkbp6, anticorps fkbp6.L, anticorps FKBP6

Sujet: Synonyms:FKBP36 Background:Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes(By similarity).

Poids moléculaire: 36 kDa

ID gène: 8468

UniProt: O75344

Pathways: M Phase