LRWD1 anticorps

N° du produit ABIN5703091

Détail du produit anti-LRWD1 anticorps

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRWD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: leucine-rich repeats and WD repeat domain containing 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur LRWD1

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Autre désignation: LRWD1 (LRWD1 Produits)

Synonymes: anticorps CENP-33, anticorps ORCA, anticorps 1200011O22Rik, anticorps AU042569, anticorps AW548074, anticorps Orca, anticorps si:dkey-261j4.9, anticorps wu:fb78b03, anticorps wu:ft31b04, anticorps leucine rich repeats and WD repeat domain containing 1, anticorps leucine-rich repeats and WD repeat domain containing 1, anticorps microRNA 5090, anticorps leucine-rich repeats and WD repeat domain containing 1 L homeolog, anticorps LRWD1, anticorps Lrwd1, anticorps lrwd1, anticorps MIR5090, anticorps lrwd1.L

Sujet: Synonyms:CENP-33, ORCA Background:Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Poids moléculaire: 85 kDa

ID gène: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding