GEMIN8 anticorps
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- Antigène Voir toutes GEMIN8 Anticorps
- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GEMIN8 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogène
- gem (nuclear organelle) associated protein 8
- Isotype
- IgG
- Top Product
- Discover our top product GEMIN8 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03423(GEMIN8 antibody) at dilution of 1:400
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
- Autre désignation
- GEMIN8 (GEMIN8 Produits)
- Synonymes
- anticorps FAM51A1, anticorps B130034M20Rik, anticorps B930082C09Rik, anticorps BC023488, anticorps gemin-8, anticorps gem nuclear organelle associated protein 8, anticorps gemin8, anticorps GEMIN8, anticorps Gemin8
- Sujet
- Synonyms:FAM51A1 Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
- Poids moléculaire
- 32 kDa
- ID gène
- 54960
- UniProt
- Q9NWZ8
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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