MMP14 anticorps (AA 100-200)

N° du produit ABIN5703940

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP14 dans WB, ELISA et IF. Il présente une réactivité envers Humain, Souris, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour MMP14 anticorps (AA 100-200) (ABIN5703940)

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-MMP14 anticorps

Épitope: AA 100-200

Fonction: MMP14 antibody

Immunogène:

Immunogen sequence: 100-200aa,Extracellular domain

Immunogen: matrix metallopeptidase 14 (membrane-inserted)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14

Sujet:

Synonyms: Matrix metalloproteinase-14 (MMP-14)|MMP-X1|Membrane-type matrix metalloproteinase 1 (MT-MMP 1, MTMMP1)|Membrane-type-1 matrix metalloproteinase (MT1-MMP, MT1MMP)|MMP14

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

ID gène: 4323

UniProt: P50281

Pathways: Autophagy