THOC6 anticorps

N° du produit ABIN5704556

Détail du produit anti-THOC6 anticorps

Antigène: THOC6 (THO Complex 6 Homolog (THOC6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THOC6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: THO complex 6 homolog (Drosophila)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

A431 cells were subjected to SDS PAGE followed by western blot with FNab08669(THOC6 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur THOC6

Antigène: THOC6 (THO Complex 6 Homolog (THOC6))

Autre désignation: THOC6 (THOC6 Produits)

Synonymes: anticorps WDR58, anticorps fSAP35, anticorps F830014G06Rik, anticorps Wdr58, anticorps Pdrp, anticorps zgc:101618, anticorps thoc6, anticorps THO complex 6, anticorps THO complex 6 homolog (Drosophila), anticorps THO complex 6 L homeolog, anticorps THOC6, anticorps Thoc6, anticorps thoc6, anticorps thoc6.L

Sujet: Synonyms:WDR58 Background:Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.

ID gène: 79228

UniProt: Q86W42