ALKBH7 anticorps

N° du produit ABIN5705608

Détail du produit anti-ALKBH7 anticorps

Antigène: ALKBH7 (AlkB, Alkylation Repair Homolog 7 (ALKBH7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: alkB, alkylation repair homolog 7 (E. coli)

Isotype: IgG

Information d'application

Indications d'application: WB :1:200-1:2000,IHC:1:20-1:200

Commentaires:

human testis tissue were subjected to SDS PAGE followed by western blot with FNab00315(ALKBH7 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur ALKBH7

Antigène: ALKBH7 (AlkB, Alkylation Repair Homolog 7 (ALKBH7))

Autre désignation: ALKBH7 (ALKBH7 Produits)

Synonymes: anticorps ABH7, anticorps SPATA11, anticorps UNQ6002, anticorps 2310045B01Rik, anticorps 2510008E23Rik, anticorps Abh7, anticorps Spata11, anticorps alkB homolog 7, anticorps Alkbh7, anticorps ALKBH7

Sujet: Synonyms:ABH7, ALKBH7, SPATA11, UNQ6002 Background:May function as protein hydroxylase, can catalyze auto-hydroxylation at Leu-110(in vitro), but this activity may be due to the absence of the true substrate(PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death(PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage(PubMed:23666923). Does not display DNA demethylase activity(PubMed:23666923). Involved in fatty acid metabolism(By similarity).

Poids moléculaire: 25kDa

ID gène: 84266

UniProt: Q9BT30