Nth Endonuclease III-Like 1 (NTHL1) anticorps
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- Antigène Voir toutes Nth Endonuclease III-Like 1 (NTHL1) Anticorps
- Nth Endonuclease III-Like 1 (NTHL1)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Inconjugué
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogène
- nth endonuclease III-like 1 (E. coli)
- Isotype
- IgG
- Top Product
- Discover our top product NTHL1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Y79 cells were subjected to SDS PAGE followed by western blot with FNab05883(NTHL1 antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- Nth Endonuclease III-Like 1 (NTHL1)
- Autre désignation
- NTHL1 (NTHL1 Produits)
- Synonymes
- anticorps psmc3, anticorps psmc3-a, anticorps nth-like DNA glycosylase 1 S homeolog, anticorps nthl1.S
- Sujet
- Synonyms:NTH1, OCTS3 Background:Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic(AP) lyase function that catalyzes the first step in base excision repair(BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine(8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
- Poids moléculaire
- 34 kDa
- ID gène
- 4913
- UniProt
- P78549
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