PDK1 anticorps (AA 107-336)

N° du produit ABIN5708184

Détail du produit anti-PDK1 anticorps

Antigène: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Épitope: AA 107-336

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids V107-Y336 was used as the immunogen for the PDK1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PDK1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the PDK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PDK1

Antigène: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Autre désignation: PDK1 / Pyruvate Dehydrogenase Kinase 1 (PDK1 Produits)

Sujet: PDK1 (Pyruvate Dehydrogenase Kinase Isoenzyme 1), is an enzyme that in humans is encoded by the PDK1 gene. To find human PDKs, Gudi et al. (1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. They identified and reported the deduced amino acid sequences of PDK1, PDK2, and PDK3. The human PDK1 gene encodes a protein with a predicted molecular mass of 49,244 Da that shares 93 % identity with that of the rat PDK1 gene. Northern blot analysis showed that the PDK1 message was expressed predominantly in the heart.

UniProt: Q15118

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Regulation of Carbohydrate Metabolic Process, Hepatitis C, L'effet Warburg