WWOX anticorps

N° du produit ABIN5708495

Détail du produit anti-WWOX anticorps

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWOX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids M1-D245 was used as the immunogen for the WWOX antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the WWOX antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the WWOX antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur WWOX

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: WWOX (WWOX Produits)

Synonymes: anticorps CG7221, anticorps DmWWOX, anticorps Dmel\\CG7221, anticorps anon-EST:Posey177, anticorps GB11795, anticorps WWOX, anticorps D16S432E, anticorps FOR, anticorps FRA16D, anticorps HHCMA56, anticorps PRO0128, anticorps SDR41C1, anticorps WOX1, anticorps zgc:55975, anticorps 5330426P09Rik, anticorps 9030416C10Rik, anticorps WW domain containing oxidoreductase, anticorps WW domain-containing oxidoreductase, anticorps Wwox, anticorps LOC411815, anticorps WWOX, anticorps CpipJ_CPIJ004939, anticorps MCYG_01584, anticorps VDBG_05631, anticorps VDBG_01326, anticorps VDBG_06753, anticorps Tsp_03967, anticorps LOC100284583, anticorps wwox

Sujet: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

UniProt: Q9NZC7