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Reticulon 4 anticorps (AA 501-515)

L’anticorps Chèvre Polyclonal anti-Reticulon 4 a été validé pour IHC et IHC (p). Il convient pour détecter Reticulon 4 dans des échantillons de Humain et Singe.
N° du produit ABIN574094

Aperçu rapide pour Reticulon 4 anticorps (AA 501-515) (ABIN574094)

Antigène

Voir toutes Reticulon 4 (RTN4) Anticorps
Reticulon 4 (RTN4)

Reactivité

  • 80
  • 55
  • 38
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Humain, Singe

Hôte

  • 76
  • 3
  • 3
  • 2
  • 2
  • 1
Chèvre

Clonalité

  • 70
  • 17
Polyclonal

Conjugué

  • 41
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Cet anticorp Reticulon 4 est non-conjugé

Application

  • 69
  • 28
  • 27
  • 23
  • 21
  • 21
  • 16
  • 12
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 16
    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-515

    Marque

    IHC-plus™

    Specificité

    Human RTN4 / Nogo. This antibody is expected to recognize reported isoform A (NP_065393.1) and isoform E (NP_997404.1).

    Homologie

    Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Panda, Horse (93%) Marmoset, Dog, Bovine, Rabbit (87%) Mouse, Rat, Bat, Pig (80%).

    Purification

    Immunoaffinity purified

    Immunogène

    Synthetic peptide C-KAQIVTEKNTSTKTS from an internal region of human RTN4 / Nogo (NP_065393.1, NP_997404.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%), Gibbon, Panda, Horse (93%), Marmoset, Dog, Bovine, Rabbit (87%), Mouse, Rat, Bat, Pig (80%).

    Type of Immunogen: Synthetic peptide
  • Indications d'application

    Approved: IHC, IHC-P (2.5 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 to 5 μg/mL

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Minimize freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    Reticulon 4 (RTN4)

    Autre désignation

    RTN4 / Nogo

    Sujet

    Name/Gene ID: RTN4
    Family: Reticulon

    Synonyms: RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP

    ID gène

    57142

    NCBI Accession

    NP_065393, NP_997404

    UniProt

    Q9NQC3

    Pathways

    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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