SIGLEC7 anticorps (PE)
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- Antigène Voir toutes SIGLEC7 Anticorps
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SIGLEC7 est conjugé à/à la PE
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Specific for human CDw328, a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.
- Purification
- Affinity purified
- Immunogène
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Monocyte-derived dendritic cells.
Type of Immunogen: Cells - Clone
- 5-386
- Isotype
- IgG1
- Top Product
- Discover our top product SIGLEC7 Anticorps primaire
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- Indications d'application
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Approved: Flo (1:1), IHC, IHC-Fr
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 1 mL distilled water.
- Concentration
- Lot specific
- Buffer
- Lyophilized powder from PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- avoid freezing
- Stock
- 4 °C
- Stockage commentaire
- 4°C, avoid freezing.
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- Antigène
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
- Autre désignation
- SIGLEC7 / CD328 (SIGLEC7 Produits)
- Synonymes
- anticorps SIGLEC7, anticorps AIRM1, anticorps CD328, anticorps CDw328, anticorps D-siglec, anticorps QA79, anticorps SIGLEC-7, anticorps SIGLEC19P, anticorps SIGLECP2, anticorps p75, anticorps p75/AIRM1, anticorps sialic acid-binding Ig-like lectin 7, anticorps sialic acid binding Ig like lectin 7, anticorps LOC468976, anticorps SIGLEC7
- Sujet
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Name/Gene ID: SIGLEC7
Family: Immunoglobulin
Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein - ID gène
- 27036
- UniProt
- Q9Y286
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