THRAP3 anticorps
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- Antigène Voir toutes THRAP3 Anticorps
- THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp THRAP3 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- A synthetic peptide of human THRAP3
- Isotype
- IgG
- Top Product
- Discover our top product THRAP3 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:1000
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))
- Autre désignation
- THRAP3 (THRAP3 Produits)
- Synonymes
- anticorps TRAP150, anticorps 9330151F09Rik, anticorps B230333E16Rik, anticorps Trap150, anticorps trap150, anticorps Thrap3, anticorps MGC132228, anticorps zgc:85716, anticorps thyroid hormone receptor associated protein 3, anticorps DNA cross-link repair 1A protein, anticorps thyroid hormone receptor associated protein 3 S homeolog, anticorps thyroid hormone receptor-associated protein 3, anticorps thyroid hormone receptor associated protein 3b, anticorps THRAP3, anticorps CpipJ_CPIJ018886, anticorps CpipJ_CPIJ019503, anticorps Thrap3, anticorps thrap3, anticorps thrap3.S, anticorps thrap3b
- Sujet
- Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC. Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition, the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex, however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes.,THRAP3,TRAP150,BCLAF2,Epigenetics & Nuclear Signaling,RNA Binding,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,THRAP3
- Poids moléculaire
- 108 kDa
- ID gène
- 9967
- UniProt
- Q9Y2W1
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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