TYK2 anticorps (pTyr1054, pTyr1055)
Aperçu rapide pour TYK2 anticorps (pTyr1054, pTyr1055) (ABIN6136278)
Antigène
Voir toutes TYK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr1054, pTyr1055
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Séquence
- EYYR
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Réactivité croisée
- Souris, Rat
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Attributs du produit
- Phosphorylated Antibodies
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Immunogène
- A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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Autre désignation
- Tyk2
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Sujet
- This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,TYK2,IMD35,JTK1,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Immunology & Inflammation,Protein phosphorylation,Tyk2
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Poids moléculaire
- 133 kDa
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ID gène
- 7297
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UniProt
- P29597
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Pathways
- Signalistation JAK/STAT, Hepatitis C
Antigène
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