CACNB4 anticorps (AA 401-520)

N° du produit ABIN6137821

Détail du produit anti-CACNB4 anticorps

Antigène: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Épitope: AA 401-520

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNB4 est non-conjugé

Application: Western Blotting (WB)

Séquence: ATHTTSSTPM TPLLGRNLGS TALSPYPTAI SGLQSQRMRH SNHSTENSPI ERRSLMTSDE NYHNERARKS RNRLSSSSQH SRDHYPLVEE DYPDSYQDTY KPHRNRGSPG GYSHDSRHRL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 401-520 of human CACNB4 (NP_000717.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CACNB4

Antigène: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Autre désignation: CACNB4 (CACNB4 Produits)

Synonymes: anticorps CAB4, anticorps CACNLB4, anticorps EA5, anticorps EIG9, anticorps EJM, anticorps EJM4, anticorps EJM6, anticorps 3110038O15Rik, anticorps Cchb4, anticorps lethargic, anticorps lh, anticorps CACNB4, anticorps cacnb4.2, anticorps calcium voltage-gated channel auxiliary subunit beta 4, anticorps calcium channel, voltage-dependent, beta 4 subunit, anticorps calcium channel, voltage-dependent, beta 4a subunit, anticorps CACNB4, anticorps Cacnb4, anticorps cacnb4.1, anticorps cacnb4, anticorps cacnb4a

Sujet: This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene.,CACNB4,CAB4,CACNLB4,EA5,EIG9,EJM,EJM4,EJM6,Signal Transduction,Neuroscience,Calcium Signaling,CACNB4

Poids moléculaire: 51 kDa/54 kDa/56 kDa/58 kDa

ID gène: 785

UniProt: O00305

Pathways: cAMP Metabolic Process, Skeletal Muscle Fiber Development