CAPN10 anticorps (AA 1-230)

N° du produit ABIN6137913

Détail du produit anti-CAPN10 anticorps

Antigène: CAPN10 (Calpain 10 (CAPN10))

Épitope: AA 1-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAPN10 est non-conjugé

Application: Western Blotting (WB)

Séquence: MRAGRGATPA RELFRDAAFP AADSSLFCDL STPLAQFRED ITWRRPQEIC ATPRLFPDDP REGQVKQGLL GDCWFLCACA ALQKSRHLLD QVIPPGQPSW ADQEYRGSFT CRIWQFGRWV EVTTDDRLPC LAGRLCFSRC QREDVFWLPL LEKVYAKVHG SYEHLWAGQV ADALVDLTGG LAERWNLKGV AGSGGQQDRP GRWEHRTCRQ LLHLKDQCLI SCCVLSPRAG

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CAPN10 (NP_075571.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CAPN10

Antigène: CAPN10 (Calpain 10 (CAPN10))

Autre désignation: CAPN10 (CAPN10 Produits)

Synonymes: anticorps CAPN10, anticorps CANP10, anticorps NIDDM1, anticorps AW049679, anticorps Capn8, anticorps mKIAA1845, anticorps calpain 10, anticorps calpain 10 L homeolog, anticorps CAPN10, anticorps capn10.L, anticorps capn10, anticorps Capn10

Sujet: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.,CAPN10,CANP10,NIDDM1,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Endocrine and metabolic diseases,Metabolic disorders,Neuroscience,Calcium Signaling,CAPN10

Poids moléculaire: 15 kDa/29 kDa/49 kDa/57 kDa/60 kDa/74 kDa

ID gène: 11132

UniProt: Q9HC96

Pathways: Positive Regulation of Peptide Hormone Secretion