Claudin 18 anticorps (AA 20-80)

N° du produit ABIN6138681

Détail du produit anti-Claudin 18 anticorps

Antigène: Claudin 18 (CLDN18)

Épitope: AA 20-80

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 18 est non-conjugé

Application: Western Blotting (WB)

Séquence: GCIAATGMDM WSTQDLYDNP VTSVFQYEGL WRSCVRQSSG FTECRPYFTI LGLPAMLQAV R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-80 of human CLDN18 (NP_057453.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Claudin 18

Antigène: Claudin 18 (CLDN18)

Autre désignation: CLDN18 (CLDN18 Produits)

Synonymes: anticorps claudin-18, anticorps CLDN18, anticorps SFTA5, anticorps SFTPJ, anticorps claudin 18 L homeolog, anticorps claudin 18, anticorps cldn18.L, anticorps CLDN18, anticorps Cldn18

Sujet: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.,CLDN18,SFTA5,SFTPJ,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN18

Poids moléculaire: 27 kDa

ID gène: 51208

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C