CTSC anticorps (AA 25-134)

N° du produit ABIN6139221

Détail du produit anti-CTSC anticorps

Antigène: CTSC (Cathepsin C (CTSC))

Épitope: AA 25-134

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTSC est non-conjugé

Application: Western Blotting (WB)

Séquence: DTPANCTYLD LLGTWVFQVG SSGSQRDVNC SVMGPQEKKV VVYLQKLDTA YDDLGNSGHF TIIYNQGFEI VLNDYKWFAF FKYKEEGSKV TTYCNETMTG WVHDVLGRNW

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 25-134 of human CTSC (NP_001805.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CTSC

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: CTSC (CTSC Produits)

Sujet: This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.,CTSC,CPPI,DPP-I,DPP1,DPPI,HMS,JP,JPD,PALS,PDON1,PLS,Cell Biology & Developmental Biology,Ubiquitin,CTSC

Poids moléculaire: 15 kDa/51 kDa

ID gène: 1075

UniProt: P53634