DNAJB14 anticorps (AA 1-120)

N° du produit ABIN6139706

Détail du produit anti-DNAJB14 anticorps

Antigène: DNAJB14 (DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14))

Épitope: AA 1-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJB14 est non-conjugé

Application: Western Blotting (WB)

Séquence: MEGNRDEAEK CVEIAREALN AGNREKAQRF LQKAEKLYPL PSARALLEII MKNGSTAGNS PHCRKPSGSG DQSKPNCTKD STSGSGEGGK GYTKDQVDGV LSINKCKNYY EVLGVTKDAG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DNAJB14 (NP_001026893.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DNAJB14

Antigène: DNAJB14 (DnaJ (Hsp40) Homolog, Subfamily B, Member 14 (DNAJB14))

Autre désignation: DNAJB14 (DNAJB14 Produits)

Synonymes: anticorps Dnajb14, anticorps MGC153638, anticorps DKFZp468H1319, anticorps EGNR9427, anticorps PRO34683, anticorps 5730496F10Rik, anticorps flj14281, anticorps DnaJ heat shock protein family (Hsp40) member B14, anticorps DnaJ (Hsp40) homolog, subfamily B, member 14, anticorps DnaJ heat shock protein family (Hsp40) member B14 S homeolog, anticorps DNAJB14, anticorps dnajb14, anticorps Dnajb14, anticorps dnajb14.S

Sujet: Acts as a co-chaperone with HSPA8/Hsc70, required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD pathway. Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70. When overexpressed, forms membranous structures together with DNAJB12 and HSPA8/Hsc70 within the nucleus, the role of these structures, named DJANGOs, is still unclear.,DNAJB14,EGNR9427,PRO34683,Epigenetics & Nuclear Signaling,Signal Transduction,DNAJB14

Poids moléculaire: 33 kDa/42 kDa

ID gène: 79982

UniProt: Q8TBM8