DUSP9 anticorps

N° du produit ABIN6139880

Détail du produit anti-DUSP9 anticorps

Antigène: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human DUSP9

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:20 - 1:200,IF,1:20 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP9

Antigène: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Autre désignation: DUSP9 (DUSP9 Produits)

Synonymes: anticorps MKP-4, anticorps MKP4, anticorps Dusp4, anticorps Mpk4, anticorps Pyst3, anticorps DUSP9, anticorps dual specificity phosphatase 9, anticorps DUSP9, anticorps Dusp9

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.,DUSP9,MKP-4,MKP4,Signal Transduction,DUSP9

Poids moléculaire: 41 kDa

ID gène: 1852

UniProt: Q99956