FOXO3 anticorps (AA 394-672)

N° du produit ABIN6140755

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXO3 dans WB, IHC et IF. Il présente une réactivité envers Souris et a été mentionné dans 3+ publications.

Aperçu rapide pour FOXO3 anticorps (AA 394-672) (ABIN6140755)

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-FOXO3 anticorps

Épitope: AA 394-672

Séquence: ALPPSQPSPP GGLMQRGSSF PYTAKSSGLG SPTGSFNSTV FGPSSLNSLR QSPMQTIQEN RPATFSSVSH YGNQTLQDLL ASDSLSHSDV MMTQSDPLMS QASTAVSAQN ARRNVMLRND PMMSFAAQPT QGSLVNQNLL HHQHQTQGAL GGSRALSNSV SNMGLSDSSS LGSAKHQQQS PASQSMQTLS DSLSGSSLYS ASANLPVMGH DKFPSDLDLD MFNGSLECDM ESIIRSELMD ADGLDFNFDS LISTQNVVGL NVGNFTGAKQ ASSQSWVPG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 394-672 of mouse FOXO3A (NP_062714.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-FOXO3 (ABIN6140755)

Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." dans: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

Liu, Cai, Hu, Mei, Zhang, Ouyang, Wang, Zhang, Xiao: "Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL)." dans: The Journal of biological chemistry, Vol. 291, Issue 49, pp. 25692-25705, (2017) (PubMed).

Yang, Wang, Xiong, Kong, Qiu, Shen, Huang: "Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes." dans: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 34, pp. 128-137, (2017) (PubMed).

Détails sur FOXO3

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FOXO3

Sujet: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.,FOXO3,AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,G1/S Checkpoint,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,FOXO3

Poids moléculaire: 71 kDa

ID gène: 56484

UniProt: Q9WVH4

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis