HLA-E anticorps (AA 22-200)

N° du produit ABIN6141842

Détail du produit anti-HLA-E anticorps

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Épitope: AA 22-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-E est non-conjugé

Application: Western Blotting (WB)

Séquence: GSHSLKYFHT SVSRPGRGEP RFISVGYVDD TQFVRFDNDA ASPRMVPRAP WMEQEGSEYW DRETRSARDT AQIFRVNLRT LRGYYNQSEA GSHTLQWMHG CELGPDGRFL RGYEQFAYDG KDYLTLNEDL RSWTAVDTAA QISEQKSNDA SEAEHQRAYL EDTCVEWLHK YLEKGKETL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 22-200 of human HLA-E (NP_005507.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HLA-E

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Autre désignation: HLA-E (HLA-E Produits)

Synonymes: anticorps EA1.2, anticorps EA2.1, anticorps HLA-6.2, anticorps MHC, anticorps QA1, anticorps major histocompatibility complex, class I, E, anticorps HLA-E, anticorps PATR-E

Sujet: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.,HLA-6.2,QA1,HLA-E,EA1.2,EA2.1,Immunology & Inflammation,HLA-E

Poids moléculaire: 40 kDa

ID gène: 3133

UniProt: P13747

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process