JAK3 anticorps (AA 750-850)

N° du produit ABIN6142642

L’anticorps Lapin Polyclonal anti-JAK3 a été validé pour WB et IF. Il convient pour détecter JAK3 dans des échantillons de Humain.

Aperçu rapide pour JAK3 anticorps (AA 750-850) (ABIN6142642)

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-JAK3 anticorps

Épitope: AA 750-850

Séquence: TELALLIQQC MAYEPVQRPS FRAVIRDLNS LISSDYELLS DPTPGALAPR DGLWNGAQLY ACQDPTIFEE RHLKYISQLG KGNFGSVELC RYDPLGDNTG A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human JAK3 (NP_000206.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur JAK3

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Autre désignation: Jak3

Sujet: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).,JAK3,JAK-3,JAK3_HUMAN,JAKL,L-JAK,LJAK,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Jak3

Poids moléculaire: 68 kDa/121 kDa/125 kDa

ID gène: 3718

UniProt: P52333

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response