LAT anticorps (AA 28-233)

N° du produit ABIN6143099

Cet anticorps Lapin Polyclonal détecte spécifiquement LAT dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour LAT anticorps (AA 28-233) (ABIN6143099)

Antigène: LAT (Linker For Activation of T Cells (LAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LAT anticorps

Épitope: AA 28-233

Séquence: HCHRLPGSYD STSSDSLYPR GIQFKRPHTV APWPPAYPPV TSYPPLSQPD LLPIPRSPQP LGGSHRTPSS RRDSDGANSV ASYENEEPAC EDADEDEDDY HNPGYLVVLP DSTPATSTAA PSAPALSTPG IRDSAFSMES IDDYVNVPES GESAEASLDG SREYVNVSQE LHPGAAKTEP AALSSQEAEE VEEEGAPDYE NLQELN

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 28-233 of human LAT (NP_001014987.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LAT

Antigène: LAT (Linker For Activation of T Cells (LAT))

Autre désignation: LAT

Sujet: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.,LAT,LAT1,pp36,IMD52,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,LAT

Poids moléculaire: 24 kDa/27 kDa/28 kDa

ID gène: 27040

UniProt: O43561

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway