LDHB anticorps (AA 1-334)

N° du produit ABIN6143128

L’anticorps Lapin Polyclonal anti-LDHB a été validé pour WB. Il convient pour détecter LDHB dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour LDHB anticorps (AA 1-334) (ABIN6143128)

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LDHB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LDHB anticorps

Épitope: AA 1-334

Séquence: MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-LDHB (ABIN6143128)

Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." dans: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." dans: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Détails sur LDHB

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Autre désignation: LDHB

Sujet: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.,LDHB,HEL-S-281,LDH-B,LDH-H,LDHBD,TRG-5,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,LDHB

Poids moléculaire: 36 kDa

ID gène: 3945

UniProt: P07195

Pathways: L'effet Warburg