MYD88 anticorps (AA 60-309)

N° du produit ABIN6128257

L’anticorps anti-MYD88 Polyclonal Lapin est utilisé pour la détection de MYD88 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour MYD88 anticorps (AA 60-309) (ABIN6128257)

Antigène: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYD88 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MYD88 anticorps

Épitope: AA 60-309

Séquence: WTALAEEMDF EYLEIRQLET QADPTGRLLD AWQGRPGASV GRLLELLTKL GRDDVLLELG PSIEEDCQKY ILKQQQEEAE KPLQVAAVDS SVPRTAELAG ITTLDDPLGH MPERFDAFIC YCPSDIQFVQ EMIRQLEQTN YRLKLCVSDR DVLPGTCVWS IASELIEKRC RRMVVVVSDD YLQSKECDFQ TKFALSLSPG AHQKRLIPIK YKAMKKEFPS ILRFITVCDY TNPCTKSWFW TRLAKALSLP

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MYD88

Antigène: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Autre désignation: MYD88

Sujet: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.,MYD88,MYD88D,myeloid differentiation primary response 88,MyD88,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,MYD88

Poids moléculaire: 15 kDa/20 kDa/28 kDa/31 kDa/33 kDa/34 kDa

ID gène: 4615

UniProt: Q99836

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades