NADPH Oxidase 4 anticorps (AA 328-578)
Aperçu rapide pour NADPH Oxidase 4 anticorps (AA 328-578) (ABIN6144752)
Antigène
Voir toutes NADPH Oxidase 4 (NOX4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 328-578
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Séquence
- KENFKARPGQ YITLHCPSVS ALENHPFTLT MCPTETKATF GVHLKIVGDW TERFRDLLLP PSSQDSEILP FIQSRNYPKL YIDGPFGSPF EESLNYEVSL CVAGGIGVTP FASILNTLLD DWKPYKLRRL YFIWVCRDIQ SFRWFADLLC MLHNKFWQEN RPDYVNIQLY LSQTDGIQKI IGEKYHALNS RLFIGRPRWK LLFDEIAKYN RGKTVGVFCC GPNSLSKTLH KLSNQNNSYG TRFEYNKESF S
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 328-578 of human NOX4 (NP_058627.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- NADPH Oxidase 4 (NOX4)
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Autre désignation
- NOX4
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Sujet
- This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.,NOX4,KOX,KOX-1,RENOX,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,Immunology & Inflammation,Cardiovascular,Blood,Heart,Cardiovascular diseases,Heart disease,NOX4
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Poids moléculaire
- 6 kDa/25-31 kDa/58-66 kDa
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ID gène
- 50507
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UniProt
- Q9NPH5
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Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
Antigène
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