PADI2 anticorps (AA 26-210)

N° du produit ABIN6145163

Détail du produit anti-PADI2 anticorps

Antigène: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Épitope: AA 26-210

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PADI2 est non-conjugé

Application: Western Blotting (WB)

Séquence: WTDVYSAAPA GAQTFSLKHS EHVWVEVVRD GEAEEVATNG KQRWLLSPST TLRVTMSQAS TEASSDKVTV NYYDEEGSIP IDQAGLFLTA IEISLDVDAD RDGVVEKNNP KKASWTWGPE GQGAILLVNC DRETPWLPKE DCRDEKVYSK EDLKDMSQMI LRTKGPDRLP AGYEIVLYIS MSDSD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 26-210 of human PADI2 (NP_031391.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PADI2

Antigène: PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))

Autre désignation: PADI2 (PADI2 Produits)

Synonymes: anticorps PADI2, anticorps PAD-H19, anticorps PAD2, anticorps PDI2, anticorps Pdi, anticorps Pdi2, anticorps mKIAA0994, anticorps peptidyl arginine deiminase 2, anticorps peptidyl arginine deiminase, type II, anticorps protein-arginine deiminase type-2, anticorps peptidyl arginine deiminase, type II S homeolog, anticorps PADI2, anticorps padi2, anticorps LOC100357368, anticorps padi2.S, anticorps Padi2

Sujet: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.,PADI2,PAD-H19,PAD2,PDI2,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,PADI2

Poids moléculaire: 49 kDa/75 kDa

ID gène: 11240

UniProt: Q9Y2J8