PPP2R2B anticorps (AA 160-260)

N° du produit ABIN6146087

Détail du produit anti-PPP2R2B anticorps

Antigène: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Épitope: AA 160-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R2B est non-conjugé

Application: Western Blotting (WB)

Séquence: KIRWLPQQNA AYFLLSTNDK TVKLWKVSER DKRPEGYNLK DEEGRLRDPA TITTLRVPVL RPMDLMVEAT PRRVFANAHT YHINSISVNS DYETYMSADD L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human PP2A-B55beta/PR55beta/PP2A-B55beta/PR55beta/PPP2R2B (NP_858060.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PPP2R2B

Antigène: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Autre désignation: PPP2R2B (PPP2R2B Produits)

Synonymes: anticorps B55BETA, anticorps PP2AB55BETA, anticorps PP2ABBETA, anticorps PP2APR55B, anticorps PP2APR55BETA, anticorps PR2AB55BETA, anticorps PR2ABBETA, anticorps PR2APR55BETA, anticorps PR52B, anticorps PR55-BETA, anticorps PR55BETA, anticorps SCA12, anticorps Pppr2b2, anticorps 2900026H06Rik, anticorps 6330404L05Rik, anticorps E130009M08Rik, anticorps PP2A-PR55B, anticorps PP2A, anticorps ppp2r2b-a, anticorps ppp2r2c, anticorps ppp2r2b, anticorps zgc:101861, anticorps PPP2R2B, anticorps protein phosphatase 2 regulatory subunit Bbeta, anticorps protein phosphatase 2, regulatory subunit B, beta, anticorps protein phosphatase 2 regulatory subunit B, beta L homeolog, anticorps protein phosphatase 2 regulatory subunit B, beta, anticorps protein phosphatase 2, regulatory subunit B, beta b, anticorps PPP2R2B, anticorps Ppp2r2b, anticorps ppp2r2b.L, anticorps ppp2r2b, anticorps ppp2r2bb

Sujet: The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12.,PPP2R2B,B55BETA,PP2AB55BETA,PP2ABBETA,PP2APR55B,PP2APR55BETA,PR2AB55BETA,PR2ABBETA,PR2APR55BETA,PR52B,PR55-BETA,PR55BETA,SCA12,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Wnt/β-Catenin Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PPP2R2B

Poids moléculaire: 50 kDa/51 kDa/52 kDa/58 kDa/62 kDa

ID gène: 5521

UniProt: Q00005

Pathways: Signalisation PI3K-Akt, Mitotic G1-G1/S Phases, Hepatitis C