PTPN13 anticorps (AA 250-500)

N° du produit ABIN6216830

Détail du produit anti-PTPN13 anticorps

Antigène: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Épitope: AA 250-500

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN13 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Séquence: QDENYFKDIL SDNSGREDSE NTFSPYQFKT SGPEKKPIPG IDVLSKKKIW ASSMDLLCTA DRDFSSGETA TYRRCHPEAV TVRTSTTPRK KEARYSDGSI ALDIFGPQKM DPIYHTRELP TSSAISSALD RIRERQKKLQ VLREAMNVEE PVRRYKTYHG DVFSTSSESP SIISSESDFR QVRRSEASKR FESSSGLPGV DETLSQGQSQ RPSRQYETPF EGNLINQEIM LKRQEEELMQ LQAKMALRQS R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human PTPN13 (NP_542416.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPN13

Antigène: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Autre désignation: PTPN13 (PTPN13 Produits)

Synonymes: anticorps FAP-1, anticorps PNP1, anticorps PTP-BAS, anticorps PTP-BL, anticorps PTP1E, anticorps PTPL1, anticorps PTPLE, anticorps hPTP1E, anticorps PTPN13, anticorps AI324989, anticorps Ptpri, anticorps RIP, anticorps Ptp-bl, anticorps ptp, anticorps wu:fb50g04, anticorps zgc:162319, anticorps protein tyrosine phosphatase, non-receptor type 13, anticorps tyrosine-protein phosphatase non-receptor type 13, anticorps PTPN13, anticorps LOC100540743, anticorps ptpn13, anticorps Ptpn13

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.,PTPN13,FAP-1,PNP1,PTP-BAS,PTP-BL,PTP1E,PTPL1,PTPLE,hPTP1E,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PTPN13

Poids moléculaire: 255 kDa/274 kDa/276 kDa/277 kDa

ID gène: 5783

UniProt: Q12923