REG4 anticorps (AA 23-158)

N° du produit ABIN6146859

Détail du produit anti-REG4 anticorps

Antigène: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Épitope: AA 23-158

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REG4 est non-conjugé

Application: Western Blotting (WB)

Séquence: DIIMRPSCAP GWFYHKSNCY GYFRKLRNWS DAELECQSYG NGAHLASILS LKEASTIAEY ISGYQRSQPI WIGLHDPQKR QQWQWIDGAM YLYRSWSGKS MGGNKHCAEM SSNNNFLTWS SNECNKRQHF LCKYRP

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 23-158 of human REG4 (NP_114433.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur REG4

Antigène: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Autre désignation: REG4 (REG4 Produits)

Synonymes: anticorps GISP, anticorps REG-IV, anticorps RELP, anticorps 2010002L15Rik, anticorps regenerating family member 4, anticorps regenerating islet-derived family, member 4, anticorps Reg4, anticorps REG4

Sujet: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.,REG4,GISP,REG-IV,RELP,REG4

Poids moléculaire: 14 kDa/18 kDa

ID gène: 83998

UniProt: Q9BYZ8