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Ribonuclease H1 anticorps (AA 1-286)

RNASEH1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6146988
  • Antigène Voir toutes Ribonuclease H1 (RNASEH1) Anticorps
    Ribonuclease H1 (RNASEH1)
    Épitope
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-286
    Reactivité
    • 15
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 10
    • 5
    Lapin
    Clonalité
    • 12
    • 3
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    Cet anticorp Ribonuclease H1 est non-conjugé
    Application
    • 12
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MSWLLFLAHR VALAALPCRR GSRGFGMFYA VRRGRKTGVF LTWNECRAQV DRFPAARFKK FATEDEAWAF VRKSASPEVS EGHENQHGQE SEAKASKRLR EPLDGDGHES AEPYAKHMKP SVEPAPPVSR DTFSYMGDFV VVYTDGCCSS NGRRRPRAGI GVYWGPGHPL NVGIRLPGRQ TNQRAEIHAA CKAIEQAKTQ NINKLVLYTD SMFTINGITN WVQGWKKNGW KTSAGKEVIN KEDFVALERL TQGMDIQWMH VPGHSGFIGN EEADRLAREG AKQSED
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human RNASEH1 (NP_002927.2).
    Isotype
    IgG
    Top Product
    Discover our top product RNASEH1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Ribonuclease H1 (RNASEH1)
    Autre désignation
    RNASEH1 (RNASEH1 Produits)
    Synonymes
    anticorps H1RNA, anticorps RNH1, anticorps 74/9, anticorps CG8729, anticorps Dmel\\CG8729, anticorps RNase H1, anticorps RnH1, anticorps l(2)43F1-5, anticorps l(2)43Fa, anticorps l(2)k07409, anticorps l(2)k07624, anticorps rnhl, anticorps h1rna, anticorps rnh1, anticorps zgc:91971, anticorps RNASEH1P1, anticorps RNASEH1, anticorps rnaseh1, anticorps Afu1g10020, anticorps Tb07.26A24.40, anticorps ribonuclease H1, anticorps ribonuclease H1 S homeolog, anticorps ribonuclease H1 L homeolog, anticorps ribonuclease HI, anticorps Ribonuclease H1, anticorps RNASEH1, anticorps Rnaseh1, anticorps rnh1, anticorps rnaseh1.S, anticorps rnaseh1, anticorps rnaseh1.L, anticorps AFUA_1G10020, anticorps Tb927.7.4930, anticorps APH_RS00510
    Sujet
    This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes, two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.,RNASEH1,H1RNA,PEOB2,RNH1,Epigenetics & Nuclear Signaling,RNASEH1
    Poids moléculaire
    32 kDa
    ID gène
    246243
    UniProt
    O60930
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