anticorps D22S673, anticorps HC2, anticorps HCF2, anticorps HCII, anticorps HLS2, anticorps LS2, anticorps THPH10, anticorps serpind1, anticorps MGC53936, anticorps rls2var1, anticorps AA985900, anticorps AI303446, anticorps Hcf2, anticorps serpin family D member 1, anticorps serpin peptidase inhibitor, clade D (heparin cofactor), member 1 L homeolog, anticorps serpin peptidase inhibitor, clade D (heparin cofactor), member 1, anticorps serine (or cysteine) peptidase inhibitor, clade D, member 1, anticorps SERPIND1, anticorps serpind1.L, anticorps Serpind1, anticorps serpind1
Sujet
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.,SERPIND1,D22S673,HC2,HCF2,HCII,HLS2,LS2,THPH10,Cardiovascular,Blood,SERPIND1