SPSB1 anticorps (AA 1-60)

N° du produit ABIN6148398

Détail du produit anti-SPSB1 anticorps

Antigène: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Épitope: AA 1-60

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPSB1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MGQKVTGGIK TVDMRDPTYR PLKQELQGLD YCKPTRLDLL LDMPPVSYDV QLLHSWNNND

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SPSB1 (NP_079382.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SPSB1

Antigène: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Autre désignation: SPSB1 (SPSB1 Produits)

Synonymes: anticorps SSB-1, anticorps SSB1, anticorps 1110014L01Rik, anticorps 4930422J18Rik, anticorps AI596360, anticorps AI854583, anticorps splA/ryanodine receptor domain and SOCS box containing 1, anticorps SPSB1, anticorps Spsb1

Sujet: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5.,SPSB1,SSB-1,SSB1,SPSB1

Poids moléculaire: 30 kDa

ID gène: 80176

UniProt: Q96BD6