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HLA-DP beta anticorps (Biotin)

HLA-DP beta Reactivité: Humain FACS, IF, IHC (f) Hôte: Souris Monoclonal Bra-14 Biotin
N° du produit ABIN6153368
  • Antigène Tous les produits HLA-DP beta
    HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
    Reactivité
    Humain
    Hôte
    • 17
    Souris
    Clonalité
    • 17
    Monoclonal
    Conjugué
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp HLA-DP beta est conjugé à/à la Biotin
    Application
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Fonction
    Mouse Monoclonal anti-MHC-II (HLA-DP beta chain) (Bra-14), Biotin Conjugate
    Attributs du produit
    This antibody recognizes a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogène
    Human REH cells
    Clone
    Bra-14
    Isotype
    IgG3 kappa
  • Indications d'application
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Commentaires

    Raji cells. Tonsil or lymph node

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Antigène
    HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
    Autre désignation
    MHC-II (HLA-DP) (beta chain) (HLA-DP beta Produits)
    Poids moléculaire
    36 kDa (? chain) and 27 kDa (? chain)
    ID gène
    3115, 3122
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