CD28 anticorps (CF®660R)

N° du produit ABIN6158519

Cet anticorps anti-CD28 est un anticorps Souris Monoclonal détectant CD28 dans FACS et IF. Adapté pour Humain, Souris, Boeuf (Vache), Porc et Mouton.

Aperçu rapide pour CD28 anticorps (CF®660R) (ABIN6158519)

Antigène: CD28

Reactivité: Humain, Souris, Boeuf (Vache), Porc, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est conjugé à/à la CF®660R

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 204-12

Détail du produit anti-CD28 anticorps (CF®660R)

Fonction: Mouse Monoclonal anti-CD28 (204.12), CF660R Conjugate

Attributs du produit: This antibody recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Stimulated human leucocytes

Isotype: IgG2a kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mLFlow Cytometry 0.5-1 μg/million cells/0.1 mL

Commentaires:

Jurkat cells or human lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: T-cell-specific surface glycoprotein CD28, Tp44

Poids moléculaire: 44 kDa (monomer), 88 kDa (dimer)

ID gène: 940, 591629

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response