CLCN2 anticorps (Internal Region)

N° du produit ABIN615956

Détail du produit anti-CLCN2 anticorps

Antigène: CLCN2 (Chloride Channel 2 (CLCN2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CLCN2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: QQLDEPVNFS DCK

Specificité: This antibody is expected to recognize all reported isoforms (NP_004357.3, NP_001164558.1, NP_001164559.1, NP_001164560.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow, Rabbit .
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_004357.3. Genename: CLCN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CLCN2

Antigène: CLCN2 (Chloride Channel 2 (CLCN2))

Autre désignation: CLCN2 (CLCN2 Produits)

Synonymes: anticorps CLCN2, anticorps CLC2, anticorps LOC100150892, anticorps AL118368, anticorps ClC-2, anticorps Clc2, anticorps nmf240, anticorps CLC-2, anticorps CIC-2, anticorps ECA2, anticorps ECA3, anticorps EGI11, anticorps EGI3, anticorps EGMA, anticorps EJM6, anticorps EJM8, anticorps clC-2, anticorps chloride voltage-gated channel 2, anticorps chloride channel, voltage-sensitive 2a, anticorps chloride channel protein 2, anticorps chloride channel, voltage-sensitive 2, anticorps CLCN2, anticorps clcn2a, anticorps EHI_142170, anticorps EHI_186860, anticorps Clcn2

Sujet: CLCN2 is a voltage-gated chloride channel, a class of proteins that have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This protein is ubiquitously expressed, with moderate expression in aortic and coronary vascular smooth muscle cells and low levels expressed in aortic endothelial cells. Defects in CLCN2 may be the cause of epilepsy with grand mal seizures on awakening, childhood absence epilepsy type 3, and juvenile absence epilepsy. Single nucleotide polymorphisms (SNPs) of CLCN2 may also at as potential modifiers of cystic fibrosis disease severity.Synonyms: CIC-2, CIC2, CLC3, Chloride channel protein 2

ID gène: 1181

NCBI Accession: NP_001164558

UniProt: P51788