EIF2S2 anticorps (pSer2)

N° du produit ABIN616039

Détail du produit anti-EIF2S2 anticorps

Antigène: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Épitope: pSer2

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2S2 est non-conjugé

Application: Western Blotting (WB)

Séquence: M-S(p)-G-D-E

Specificité: This antibody detects endogenous levels of eIF2β only when phosphorylated at serine 2.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Affinity-chromatography using epitope-specific peptide

Immunogène: Peptide sequence around phosphorylation site of serine 2 derived from eIF2beta.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur EIF2S2

Antigène: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Autre désignation: EIF2B / EIF2S2 (EIF2S2 Produits)

Synonymes: anticorps EIF2, anticorps EIF2B, anticorps EIF2beta, anticorps PPP1R67, anticorps eIF-2-beta, anticorps 2810026E11Rik, anticorps 38kDa, anticorps AA408636, anticorps AA571381, anticorps AA986487, anticorps AW822225, anticorps D2Ertd303e, anticorps zgc:77084, anticorps wu:fc26g03, anticorps wu:fu10f07, anticorps MGC130959, anticorps DDBDRAFT_0205105, anticorps DDBDRAFT_0234112, anticorps DDB_0205105, anticorps DDB_0234112, anticorps AO090005001412, anticorps eukaryotic translation initiation factor 2 subunit beta, anticorps eukaryotic translation initiation factor 2, subunit 2 (beta), anticorps eukaryotic translation initiation factor 2, subunit 2 beta, anticorps eukaryotic translation initiation factor 2 subunit beta L homeolog, anticorps eIF-3 beta, anticorps hypothetical protein, anticorps eukaryotic translation initiation factor 2 subunit 2, anticorps EIF2S2, anticorps Eif2s2, anticorps eif2s2, anticorps eif2s2.L, anticorps eIF2s2, anticorps TP02_0678, anticorps EDI_093670, anticorps AOR_1_2450174, anticorps MGYG_05853, anticorps PGTG_10708, anticorps LOC101111733

Sujet: EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.Synonyms: Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, eIF2-beta

Poids moléculaire: 38 kDa

ID gène: 8894

NCBI Accession: NP_003899

UniProt: P20042