Integrin beta 2 anticorps (CF®405S)

N° du produit ABIN6169016

Cet anticorps anti-Integrin beta 2 est un anticorps Souris Monoclonal détectant Integrin beta 2 dans FACS et IF. Adapté pour Humain.

Aperçu rapide pour Integrin beta 2 anticorps (CF®405S) (ABIN6169016)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est conjugé à/à la CF®405S

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 68-5A5

Détail du produit anti-Integrin beta 2 anticorps (CF®405S)

Fonction: Mouse Monoclonal anti-CD18 (68-5A5), CF405S Conjugate

Attributs du produit: This antibody recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Stimulated human leukocytes

Isotype: IgG2a kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Lymphocytes, granulocytes, and macrophages in tonsil or lymph node.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: CD18

Poids moléculaire: 95 kDa

ID gène: 3689, 375957

UniProt: P05107

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation